CFD Research Corp., Huntsville, Alabama, has been awarded a $24,547,621 cost-plus-fixed-fee contract for Airman readiness medical research in-silico framework to evaluate toxicity of hazardous materials. This contract provides for research, development, and validation of a broad in-silico framework for toxicity risk assessment of Air Force-relevant hazardous materials and contaminants. Work will primarily be performed in Huntsville and is expected to be completed May 7, 2027. Fiscal 2022 research, development, test and evaluation funds in the amount of $1,000,000 will be obligated at the time of award. Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio, is the contracting activity (FA2384-23-C-0003).