The Domestic Nuclear Detection Office (DNDO) has issued a Request for Information (RFI) from industries that have the potential to produce Helium-3 from natural helium and or from any source. DNDO is a member of the He-3 Integrated Product Team, which consists of representatives across the U.S. government that have the goal to manage the reserves of He-3 that has many critical applications such as medical imaging, oil and gas exploration, scientific research, and one dominant application being neutron detection. The supplies of He-3 are decreasing while demand is increasing worldwide. DNDO says two industrial businesses appear to offer the best opportunity to make up for the He-3 shortfall: crude helium process plants at the Cliffside Fields along the conservation pipeline where helium liquefaction already occurs; and extraction of He-3 from trace elements when processing natural gas. The desired requirement within the U.S. is estimated to be more than 50,000 liters per year and growing. The severe He-3 shortage is affecting production of radiation portal monitors in the U.S. (TR2, Nov. 25). Sol. No. RFI_He3. Respond by Jan. 18, 2010. Contact: Margo Graves, contracting officer, 202-254-7572, [email protected].