The Defense Threat Reduction Agency (DTRA) has issued a Sources Sought notice related to its requirement to build upon an existing experimental research and development computing platform and prototype for a system capability that provides detail and performance in scalable agent-based epidemiological models and co-evolving infrastructures in energy, transportation, and telecommunications systems. The capability will be used by Defense Department planners and policymakers for analysis and optimal responses with primary, secondary and tertiary effects of a weapon of mass destruction insult on critical infrastructures in near-real time using high-performance computers. The technology developed for the capability will represent hundreds of millions of individual agents interacting with each other, each agent moving among millions of locations in hundreds of communities and regions possessing independent critical infrastructures computed in seconds in a simulated infrastructure. The technology will be able to provide direct operational support to warfighters, first responders, and such events as the swine flu pandemic for determining situational awareness and the best course of action for mitigating the spread of infection among the population. Sol. No. TSD109919796. Respond by Sept. 9. Contact: Mary Kay Chase, [email protected].